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More Medical News
18 Feb 2009
A widely available drug is capable of preventing withdrawal symptoms associated with opioids, scientists have discovered.
Ondansetron, which is used to treat nausea and vomiting, could prevent the problems that occur in people who are addicted to the powerful painkillers.
Lead author Larry Chu, assistant professor of anesthesia at Stanford University School of Medicine, US, said that opiod abuse is "rising at a faster rate than any other type of illicit drug use".
"One barrier to treatment is that when you abruptly stop taking the drugs, there is a constellation of symptoms associated with withdrawal," he said.
Opioids cover a range of prescription and illegal drugs, including morphine and heroine. According to the National Survey on Drug Use and Health in the US, around 12.5 million Americans used prescription pain drugs for non-medical reasons in 2007.
Scientists found that ondansetron is capable of blocking certain receptors that are associated with opioid withdrawal symptoms.
Ondansetron works by limiting the activity of the vagus nerve. It also blocks serotonin receptors in the chemoreceptor trigger zone.
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GLUCOBAY - 41.89%
... HbA1, HbA1c). The changes may be a reduction or reduced deterioration in HbA1 or HbA1c levels, depending upon the patient's clinical status and disease progression. These parameters are affected in a dose-dependent manner by Glucobay. Following oral administration, only 1-2% of the active inhibitor ... -
TRITACE Tablets - 37.31%
... revascularisation procedures in patients of 55 years or more who have clinical evidence of cardiovascular disease (previous MI, unstable angina or multivessel CABG or multivessel PTCA), stroke or peripheral vascular disease. Also for reducing the risk of myocardial infarction, stroke, cardiovascular ... -
TRITACE Titration Pack - 37.13%
... revascularisation procedures in patients of 55 years or more who have clinical evidence of cardiovascular disease (previous MI, unstable angina or multivessel CABG or multivessel PTCA), stroke or peripheral vascular disease. Also for reducing the risk of myocardial infarction, stroke, cardiovascular ... -
ZYLORIC - 36.47%
... clinical risk (e.g. treatment of malignancy potentially leading to acute uric acid nephropathy). The main clinical conditions where urate/uric acid deposition may occur are: idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high ... -
ZAPAIN - 36.21%
... with: manifest atherothrombotic cardiovascular disease (history of coronary heart disease or stroke, or peripheral vascular disease) or diabetes with at least one cardiovascular risk factor. - Treatment of renal disease: Incipient glomerular diabetic nephropathy as defined by the ... -
NAGLAZYME Solution for Infusion - 35.67%
... to initiate treatment as early as possible, before appearance of non-reversible clinical manifestations of the disease. A key issue is to treat young patients aged <5 years suffering from a severe form of the disease, even though patients <5 years were not included in the pivotal phase 3 study ...

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